Intermodal transport refers to the method of transporting goods using two or more different modes of transportation, such as rail, truck, ship, or airplane, in a single journey without handling the cargo itself when changing modes. The cargo is packed into an Intermodal Loading Unit (ILU) which might be a maritime (tank) container, continental swap body or (craneable) semi-trailer. This guideline is a joint initiative of three major associations (ECTA, ERFA and UIRR) active in freight with the objective to promote the modal shift of chemical substances from road to rail. This guideline aims at providing a path towards an integrated standardized digital ecosystem in intermodal freight transport.